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finasteride has been approved for the treatment of the male pattern baldness as Propecia
prescription 1 mg / day.
Dr. Mary Sawaya says that Propecia is a very sure medicine
and with a low incidence of collateral effects.
In some countries the price of Propecia has raised
decidedly, compared with other countries of the world.
It doesn't act against the androgens, but selectively
against the formation of the DHT, inhibiting the enzyme 5-alfa-reductasi that allows
the transformation of the testosterone in DHT (toxic for the hair). A single tablet of
Proscar decreases DHT's percentage in the blood of the 80%. The absorption has not
influenced by food. The emi-life in blood is of around 6 hours.
The finasteride inhibits the type 2 of
5-alfa-reductasi (not type 1).
Type 1 is primarily contained in the sebaceus glands of a
lot of zones of the skin, included scalp and liver; the type 2 are instead contained
primarily in the prostate , seminal vesicles, epididimo, the hair's follicles, liver.
The type 1 are responsible for 1/3 of the whole circulating
DHT while the type 2 are responsible of the 2/3 and it is the contained type in the
follicles, that's why the drug works well.
In two years of clinical studies in men (more than 1800) of
inclusive age in 18 and 41 years Propecia has shown of: to maintain and to increase hair
count of 83%.
The collateral
effects in the male are rare, reduced at 4%
and are underlined with light decrease of the sexual desire, impotence, diminution of the
libido and the spermatic volume. All reversing effects however with suspension. As all the
synthetic medicines, are not a perfect medicine and however the collateral effects are
rare, while in other medicines are more frequent.
The contemporary assumption of Roaccutane (isotretinoina)
is dissuaded, since the medicine can oppose the effect of Propecia.
It is dangerous for the woman in pregnancy, since it
influences on the development of the genital of the virile fetus.
The women in fertile age don't have to assume the drug,
while this can have been doing with calm and with some result, by women after menopause.
Propecia can influence (distort) an examination of the
blood called PSA (antigen specific prostate).
Topical use seems not effective, there are not studies that prove
the effectiveness, rather some study has underlined systemic absorption of the finasteride
topically applied, that induce to think that the also modest gotten results are due to the
absorbed finasteride in body. The Merck would have almost certainly developed a topical
lotion instead of a pill.
It is with combined use of finasteride and minoxidil that
the best results are observed in quality, quantity and time.
Then logic is "Propecia + topical solution."
It is necessary however to consider to strike the baldness
androgenetica with different anglings, therefore to act with a growth stimulator as the minoxidil and the different products SOD (that also act on the factor autoimmune) to get
the maximum benefit in the small possible time.
You can also read chapter
It is possible to prevent that the body is accustomed to
the action of the finasteride moving the time of the assumption every 3-4 months.
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